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MK Dons are the most in-form side in League One at the moment, having avoided defeat in their last 10 games, with their last five outings resulting in maximum points.
In fact, no side has collected more points in League One in 2022 than the Dons, who have lost just one of their 15 league games in the current calendar year.
In midweek, they claimed a 3-1 home victory over Cheltenham Town thanks to a Troy Parrott brace and a Mo Eisa strike.
Despite their impressive run of results, Liam Manning will view Saturday’s home contest as a must-win game if his side are to have realistic ambitions of clinching automatic promotion to the Championship.
Having scored at least two goals in their last five fixtures, MK Dons will be confident that they have the resources to test one of the best defences in League One on Saturday.
Aden Baldwin is ruled out for the hosts, while there are doubts over Connor Wickham and Tennai Watson who have both picked up knocks.
Manning is expected to bring Scott Twine back into the starting lineup after the 22-year-old dropped down to the bench for the midweek contest.
Meanwhile, Eisa will be aiming to score for a fourth consecutive game when he leads the line for the Dons on Saturday.
Wigan are without the services of Thelo Aasgaard and Jordan Cousins, who are both long-term absentees.
Glen Rea is expected to miss out after picking up a knee problem last weekend, while Jason Kerr is also ruled out due to an injury issue.
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After making a number of changes for the EFL Trophy semi-final, Richardson is expected to name a similar starting lineup to the one that began the contest with AFC Wimbledon last Saturday.
MK Dons possible starting lineup:
Cumming; O’Hora, Darling, Lewington; Corbeanu, Smith, Coventry, Kesler; Twine, Parrott, Eisa
Wigan Athletic possible starting lineup:
Amos; Power, Whatmough, Watts, Darikwa; Naylor, Shinnie; Lang, Keane, Edwards; Humphrys