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James McClean, Tendayi Darikwa and Graeme Shinnie are all suspended as Wigan host AFC Wimbledon in Sky Bet League One.
Republic of Ireland international McClean is beginning a three-game ban for his sending-off against Fleetwood while captain Darikwa and Shinnie must sit out the next two matches after reaching 10 bookings for the season.
Tom Pearce and Joe Bennett are back in contention after injury but Luke Robinson (ankle) is a doubt and Jason Kerr (foot) is out.
Charlie Wyke this week gave a positive update on his heart condition but is due to undergo a procedure and will not play again this season.
Wimbledon captain Alex Woodyard looks set to continue for the visitors after a successful return to action last weekend.
The midfielder played the full 90 minutes of the 2-2 draw with Doncaster in a first appearance for a month after a hamstring problem.
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The ‘Tics sit seven points behind Rotherham in the league table going into this weekend and are three points above 3rd place MK Dons with two games in hand.
Liam Manning’s men are in fine form at the moment and are breathing down the Latics’ neck. However, Richardson’s side just need to focus on themselves and have been consistently picking up points over recent times.
AFC Wimbledon make the trip to the DW Stadium fighting for their lives near the bottom of the division. They are in 20th place and are two points above the relegation zone after drawing 2-2 with Doncaster Rovers in their last match.