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Having recorded just one goal and one point from his first five matches at West Brom, this is the worst start that Steve Bruce has made to any of his 12 managerial jobs.
If the Championship season had started when the 61-year-old was appointed, the Baggies would be 23rd in the table and only above Peterborough United on goal difference.
A 2-0 home defeat to Swansea City on Monday left the Midlands outfit eight points adrift of the playoffs with 12 games left to play.
West Brom have lost six consecutive matches away from home and have not won on the road since the beginning of December.
However, they still have the third-best defence in the Championship and have won their last four meetings with Hull, with Karlan Grant scoring the only goal of the game in a 1-0 victory at The Hawthorns in November.
Callum Elder, Marcus Forss, Allahyar Sayyadmanesh and Tom Eaves are all set to be in contention for Hull after recovering from their respective injuries.
With three forwards returning, Arveladze will have a selection headache in attack given that Smith and Lewis-Potter got on the scoresheet last weekend.
Goalkeeper Nathan Baxter remains sidelined with a hand injury, meaning that Matt Ingram will continue between the sticks.
West Brom will be boosted by the return of captain Jake Livermore, who has been suspended for the last four matches.
Matt Phillips is likely to remain absent as he waits for a stress fracture in his toe to heal, while Daryl Dike continues to be a big miss for the Baggies.
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Grant will be pushing to return to the starting lineup after dropping out for Callum Robinson on Monday night.
Hull City possible starting lineup:
Ingram; Jones, Greaves, McLoughlin; Slater, Docherty, Smallwood, Fleming; Lewis-Potter; Forss, Smith
West Bromwich Albion possible starting lineup:
Johnstone; Furlong, Ajayi, Bartley, Townsend; Reach, Livermore, Mowatt; Diangana, Carroll, Grant